Hcl 2h 2 o component approximate percent by weight cas number rtecs number ondansetron hydrochloride dihydrate 0. Read the medication guide provided by your pharmacist before you start taking metoclopramide and each time you get a refill. Metoclopramide base as the monohydrochloride monohydrate, bp 5 mg material identification and information. That research project also produced the product sulpiride. Sodium hydroxide andor hydrochloric acid may be added to adjust.
Emergency overview metoclopramide metoclopramide hydrochloride injection is a solution containing metoclopramide hydrochloride, a selective dopamine antagonist that increases gut motility. Metoclopramide oral tablet is a prescription drug thats available as the brandname drugs reglan and metozolv odt. Packaging and storage preserve in tight, lightresistant containers. Metoclopramide hydrochloride injection, usp simplist. Chemically, it is 4amino5chloron2diethylaminoethyl2methoxy benzamide monohydrochloride monohydrate. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Metoclopramide oral solution, usp other means of identification product codes.
It has a role as an antiemetic, a dopaminergic antagonist, a gastrointestinal drug, a xenobiotic and an environmental contaminant. It stimulates the motility of the upper gastrointestinal tract without affecting gastric, biliary, or. Metoclopramide is a member of the class of benzamides resulting from the formal condensation of 4amino5chloro2methoxybenzoic acid with the primary amino group of n,ndiethylethane1,2diamine. Poison control center 18009221117 active ingredients. Crcl jul 16, 2015 dosing information of metoclopramide hcl for dogs and cats medication should never be administered without first consulting your veterinarian. On this page about metoclopramide hydrochloride apo you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme pbs as well as other useful information. Empirical formula hill notation c 14 h 22 cln 3 o 2 hcl. Reglan, metozolv odt metoclopramide dosing, indications. Capitals indicate lifethreatening, underlines indicate most frequent. The catalog displays all strengths and sizes along with the description, imprint code, ndc and photo for each product. Feb 11, 2016 metoclopramide is a dopaminergic blocker, acting as a delayed gastrointestinal emptying adjunct and as a peristaltic stimulant. In dogs and cats, the typical dose administered is 0.
Metoclopramide hydrochloride metoclopramide hydrochloride. Description of first aid measures general information get medical adviceattention if you feel unwell. Metoclopramide hydrochloride cas 7232215 scbt santa. Mouse oral ld50 4000 mgkg metoclopramide sodium hydroxide version. Metoclopramide hydrochloride safety data sheet according to regulation ec no. Metoclopramide was first described by louis justinbesancon and charles laville in 1964, while working to improve the antidysrhythmic properties of procainamide. Immediately flush eyes with plenty of water for at least 15 to 20 minutes. Nov 20, 2019 metoclopramide 10mg tablets patient information leaflet pil by accorduk ltd. Metoclopramide has been reported to cause rare instances of clinically apparent liver injury, but the clinical features have not been well described. November 18, 2014 145, julesleger boucherville, qc, canada j4b 7k8 control no. Chemically, it is 4amino5chloron2diethylaminoethyloanisamide monohydrochloride monohydrate. Hazards identification emergency overview marcaine bupivacaine hydrochloride with epinephrine injection is. Find its price or cost, dose, when to use, how to use, side effects, adverse effects, substitutes.
Inhalation remove person to fresh air and keep comfortable for breathing. Metoclopramide is distributed into breast milk, and it crosses the bloodbrain barrier and the placenta. Buy metoclopramide hydrochloride cas 7232215, a d2dr inhibitor and an htr3e inhibitor, from santa cruz. Metoclopramide injection metoclopramide dose, indications. It is also used to relieve the symptoms of slow stomach emptying in people with diabetes. Metoclopramide side effects, dosage, uses, and more. Metoclopramide hydrochloride injection page 1 of 18 product monograph prmetoclopramide hydrochloride injection sandoz standard 5 mgml modifier of upper gastrointestinal tract motility antiemetic sandoz canada inc. Hazard information carcinogen list substance iarc ntp osha metoclopramide hydrochloride monohdyrate not listed not listed not listed emergency overview metoclopramide metoclopramide hydrochloride injection is a solution containing. Hazardous ingredients present at less than 1% may include sodium chloride, methylparaben, nf and propylparaben, nf. Metoclopramide hydrochloride is a white crystalline, odorless substance, freely soluble in water.
Metoclopramide met oh kloe pra mide is used to treat the symptoms of gastroesophageal reflux disease gerd like heartburn. Metoclopramide is an oral prokinetic and antiemetic agent used in the therapy of gastroesophageal reflux disease, gastroparesis and severe or chemotherapy induced nausea. Safety data sheet product name marcaine bupivacaine. Metoclopramide hydrochloride metoclopramide hydrochloride this product information is intended only for residents of the united states. Metoclopramide hcl cas rn 54143576 metoclopramide hydrochloride. This material is for use as an adjunct to general anesthesia producing sedation, stabilizing heart rate and blood pressure, and producing analgesia. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Metoclopramide hcl metoclopramide hcl monohydrate metoclopramide hydrochloride metoclopramide monohydrochloride monohydrate unii w1792a2rvd cas number 54143576 weight average. Hazardous ingredients present at less than 1% may include sodium chloride. It blocks type 2 dopamine receptors and 5ht 3 serotonin receptors when used in higher doses used to prevent cinv in the chemoreceptor trigger zone, increases lower esophageal sphincter tone, and enhances bowel and gastric motility. Metoclopramide comes as a tablet, an orally disintegrating dissolving tablet, and a solution liquid to take by mouth. Metoclopramide is indicated in children aged 118 years if other treatment does not work or cannot be used to prevent delayed nausea and vomiting that may occur after chemotherapy.
Metoclopramide hydrochloride is a white or practically white, crystalline, odorless or practically odorless powder. Metoclopramide hydrochloride 5mg5ml oral solution summary. Metoclopramide produces sedation and may produce extrapyramidal reactions, although these are comparatively. Does metoclopramide hcl interact with other medications. Identification of the substancepreparation and the companyundertaking ghs product identifier product name. Metoclopramide hydrochloride contains not less than 98. Metoclopramide hydrochloride safety data sheet section 2. Dronca, charles loprinzi, in management of cancer in the older patient, 2012. Dailymed metoclopramide metoclopramide hydrochloride solution. Dailymed metoclopramide metoclopramide hydrochloride. What metoclopramide hydrochloride 5mg5ml oral solution is and what it is used for the name of your medicine is metoclopramide hydrochloride 5mg5ml oral solution known as metoclopramide in this leaflet. Metoclopramide 10mg tablets patient information leaflet.
Dec 28, 2018 metoclopramide hydrochloride is a white or practically white, crystalline, odorless or practically odorless powder. After an overnight fast and having abstained from alcohol for at least 48 h, subjects received metoclopramide as a 10 mg intravenous bolus, or as a tablet containing 10 mg metoclopramide hydrochloride, equivalent to 8. Diphenhydramine hydrochloride or benztropine mesylate may be used to treat these adverse reactions. Dec 12, 2017 the molecular formula is c 14 h 22 cln 3 o 2 hclh 2 o. Nonhazardous ingredients include water for injection and sodium citrate. Avoid reglan in patients receiving other drugs that can. Material may be irritating to the mucous membranes and upper respiratory tract. Metoclopramide hydrochloride definition of metoclopramide. Metoclopramide 10mg tabs teva the harvard drug group. Material safety data sheet of metoclopramide hydrochloride. It is usually taken 4 times a day on an empty stomach, 30 minutes before each meal and at bedtime. Metoclopramide is a dopaminergic blocker, acting as a delayed gastrointestinal emptying adjunct and as a peristaltic stimulant. Metoclopramide hydrochloride solid cas number 7232215. For research use only, not for human or veterinary use.
Dexmedetomidine hydrochloride injection product userestriction. Metoclopramide is the most commonly used drug in this class. Chemical product and company identification msds number. The product catalog provides you with a full listing of tevas brand and generic product lines. Metoclopramide is only weakly bound to plasma protein about 30%.
Metoclopramide 10mg tablets patient information leaflet pil by accorduk ltd. Metoclopramide is administered orally and parenterally. Identification of the substancemixture and of the companyundertaking product name. Product name metoclopramide hydrochloride cas number 54143576 chemical formula chcln. The molecular formula is c 14 h 22 cln 3 o 2 hclh 2 o. Reglan injection metoclopramide injection, usp is a clear. How to store metoclopramide hydrochloride 5mg5ml oral solution 6. When metoclopramide is used to treat symptoms of gerd, it may be taken less frequently, especially if symptoms only occur at. Metoclopramide oral solution usp is an orangecolored, berrycitrus flavored liquid for oral administration and is available in 10 mg10 ml oral solution.
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